Fungal Diversity and Yeast Patterns of Yeast Sensitifity to Several Antifungals in Jakarta

Abstract

Fungal infections are common in the tropics. The cause of mycoses depends on the cause and the accompanying risk factors. It is important to do culture and identification to determine the etiology and continue with antifungal sensitivity examination to determine the appropriate management. The method of treating a yeast infection depends on the type of infection, its severity and the part of the body that is infected. As various fungi cause infections, the antifungal drugs used are also very diverse. The study was conducted during 2020 consisting of  350 samples of various specimens with positive cultures of 116 (33.14%). The results of identification using Vitek 2^®   automated system and slide culture obtained 19 species on fungus, consistinf of 99.14% yeast and  0.87% mold. The most yeast found were C. albicans 26.27%  and Aspergillus sp;  Rhizopus  0.86 %  respectively from mold. The pattern of sensitivity of yeast to several antifungals showed that Fluconazole was effective at 96.43%, followed Voriconazole and Amphothericin B 93.24% respectively. The next are Flucytocin, Micafungin and Caspofungin 91.66%,  86.18% and 85.74% respectively. Culture, identification and sensitivity examination need to be improved to obtain images and information that reflects.

Keywords : yeast, mold, sensitivity patterns, antifungal